Endocrine Abstracts

Introduction: Lipohypertrophy (LH) is a chronic complication of diabetes mellitus that caused by frequent subcutaneous injections of insulin. Nowadays, on the basis of results of ultrasonography of subcutaneous fat prevalence of LH in diabetic patients is still high.Design: The aim has been to develop prevention of insulin induced LH in diabetic patients. This study was done on 140 diabetic patients who had been under the treatment with insulin a mean 8 ...

The purpose: To estimate the frequency of appearance of different risk factors for the DKA (diabetic ketoacidosis) developing in a real clinical practice in Rostov-on-Don.Materials: Patients who had a diagnosis of DKA.Methods: Survey about the character of nutrition, alcohol drinking and other risk factors.Design: All patients were divided into two groups according to their age. The first group-12 patients yo...

The aim of the study was to defined the level of rehabilitation after the stroke depending on the type of hyperglycemia.Materials and methods: The retrospective analysis of 122 (54 female and 68 men) cases of ischemic stroke (IS) has been done. The diagnosis of IS was confirmed by computer tomography. According to the level of hyperglycemia at the debut of IS the patients were divided into three groups. Group 1 (60 patients) – with normoglycemia, gr...

Background: Adrenal insufficiency (AI) in pregnant women is difficult to manage because of similarity between clinics of decompensation of AI and gestational toxicosis. Objective difficulty is absence of clinical guidelines of management of pregnant patients with AI. We present a clinical case where the management of pregnant patient was not careful, which led to overdose and iatrogenic hypercortisolism.Clinical case: Pregnant woman, 29years old, asked s...

Background: Pheochromocytoma (Ph) is the tumor that is fatal if do not suspect and treat it on time. It is supposed that size of tumor is correlated with its synthetic activity. Here we present a clinical case of giant Ph with low synthetic activity that could have been recognized as adrenal cancer, which, in turn, may have led to wrong treatment.Clinical case: Young woman, 28 years old, presented with the adrenal incidentaloma. She had not any complaint...

Introduction: Lipohypertrophy (LH) is a chronic complication of diabetes mellitus that caused by frequent subcutaneous injections of insulin. Nowadays, LH were modified due to good quality modern insulin and expansion their concentration. As a result, some difficulties of diagnosis were appeared.Design: The aim of this study has been to develop the estimation risk model of insulin induced LH in diabetic patients. This study was done on 140 diabetic patie...

Background: Schwannoma (Sch) is a rare peripheral nerve sheath tumor comprised entirely of neoplastic Schwann cells. Adrenal Sch are extremely rare. Most adrenal Sch are incidental, and patients with Sch may not have any complaints. Here we present the clinical case of giant adrenal Sch, which caused hematuria and had indiscriminating organ origin on MRI.Clinical case: Woman, 58 y.o., was consulted by urologist because of painless macrohematuria. Abdomen...

Introduction: Lipohypertrophy (LH) is a chronic complication of diabetes mellitus that caused by frequent s.c. injections of insulin. Nowadays, LH were modified due to good quality modern insulin and expansion their concentration. As a result, some difficulties of diagnosis were appeared.Design: The aim of this study has been to compare the frequency of insulin induced LH in diabetic patients revealed by ultrasonography of subcutaneous fat with those fou...

Introduction: Amyloid goitre is a rare cause of thyroid enlargement, especially as a reason of fast growth. Here we present unusual case of idiopathic AA-amyloidosis as a cause of rapidly growing goitre.Clinical case: Patient 36-year-old presented with complaints of shortness of breath and deglutitive problems during 2 months. His medical history was notable for nephrotic syndrome due to AA-amyloid nephropathy and chronic hepatitis C that were diagnosed ...

Obesity is a polyetiological and incompletely studied disease. Recent publications link the special composition of the gut microbiota not only with obesity, but also with its metabolic profile1, 2. To study the characteristics of the gut microbiota in patients with different phenotypes of obesity, 37 patients were examined. In addition to determining the quantitative composition of the gut microbiota by the Real-time PCR method, all participants were determined by l...